I have wasted several hours on this issue and only made the problem worse. Originally only Photoshop CC 2018 would not launch and I would get the above message. After following Adobe online instructions for Error: 16, now all my CC apps won't launch. There is no ability to call support or chat.
I have the CC 2018 Photography plan and Premier Pro CC on a Windows 10 Pro modern machine. The install was previously working, but I now have the same error on launch.
I have done the instructions in this at least 3 times:
Configuration error in Adobe Creative Cloud
I have run the CC Cleaner Tool several times:
Use the Creative Cloud Cleaner Tool to solve installation problems
My products are correctly activated to the machine that I am using.
I can launch the app by finding the icon and right clicking open as administrator, but this is not a proper solution. For example, I can't launch a photo from lightroom to photoshop this way.
Any suggestions?